Chemotherapy and Radiation Therapy Practice Test

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• Destruction of neutrophils is most closely linked with which of the following?
• Which endocrine therapies are used for hormone receptor-positive breast cancer?
• Name a common late effect of pelvic radiotherapy.
• Which of the following should be expected when caring for a patient with chemotherapy-induced nephrotoxicity?
• Stomatitis from chemotherapy is primarily a problem related to which tissue?
• Which statement about intraarterial chemotherapy administration is correct?
• Which action demonstrates understanding of the planning phase for radiation therapy?
• In cisplatin hydration protocols, which adjunct is sometimes used with aggressive IV fluids to further reduce nephrotoxicity?
• Which statement describes standard management for mucositis?
• Which route involves delivering chemotherapy directly into arteries feeding a tumor?
• The term for painful swallowing is which?
• Which drug is an immune checkpoint inhibitor used in cancer therapy?
• Which symptom is commonly monitored as a chemotherapy-related mucositis complication?
• Irritant chemotherapy drugs are known to...
• Which statement best describes late or long-term effects of chemotherapy?
• Which statement would be appropriate to include in stomatitis teaching for a chemotherapy patient?
• After lumpectomy in breast-conserving therapy, what radiation field design is typical?
• Chemotherapy-induced cell destruction can lead to increased uric acid levels, potentially causing which complications if not managed?
• In monitoring kidney function during chemotherapy, which parameter is most directly assessed?
• Destruction of neutrophils increases risk of what?
• Antimetabolites primarily act during which phase of the cell cycle?
• BE P chemotherapy regimen includes Bleomycin, Etoposide, and Cisplatin; standard for which disease?
• The alpha/beta ratio used in BED calculations reflects tissue sensitivity to fractionation. Which statement is true?
• Which imaging modality is used to assess metabolic response to therapy?
• How does mucositis present and how is it managed?
• Allopurinol may be given as a prophylactic measure to prevent which chemotherapy-related complication?
• Which statement best reflects the purpose of allopurinol in chemotherapy patients?
• Why is leucovorin rescue used with high-dose methotrexate?
• In RECIST v1.1, what defines a partial response?
• How do alkylating agents primarily damage cancer cells?
• What is the significance of the dose-volume histogram (DVH) in radiotherapy planning?
• Antitumor antibiotics exert their effects by which mechanism?
• Dysgeusia refers to which condition?
• What does PTV stand for in radiotherapy planning?
• The term for loss of appetite is which?
• Which cardiac complication can occur as an acute toxicity of some chemotherapy regimens?
• In radiotherapy, what is the purpose of dose fractionation?
• Which effect would the nurse monitor for in a patient who had chemotherapy treatment 8 days ago?
• Which nursing intervention would the nurse include for a patient with radiation-induced skin changes?
• Which regional route delivers chemotherapy into the peritoneal cavity?
• Which term best describes delivering chemotherapy drugs directly to a body region rather than systemically?
• Which tumor type is reported to respond best to radiation therapy?
• The symptom described by the term xerostomia is which of the following?
• Which statement best differentiates Taxanes from Vinca alkaloids?
• Topoisomerase inhibitors function by inhibiting topoisomerases, which normally perform what role?
• Antimetabolites such as 5-fluorouracil work by what mechanism, and what is a common toxicity?
• Which skin-care instruction is appropriate for a patient receiving radiation therapy?
• Which statement would you expect to hear in teaching for intraarterial chemotherapy administration?
• Tumor lysis syndrome metabolic disturbances include which?
• Bevacizumab belongs to which class of cancer drugs?
• Central Venous Access Device (CVAD) characteristics include which of the following?
• Which imaging approach is commonly used to plan radiotherapy and verify patient alignment?
• Which intervention would the nurse expect to perform when caring for a patient experiencing nephrotoxicity as a result of chemotherapy treatment?
• What is the role of amifostine in radiotherapy?
• External beam radiation therapy is delivered from which location?
• What is the purpose of growth factor support during chemotherapy?
• Name two growth factors used to support chemotherapy-related neutropenia.
• Which statement describes how to palliate pain in stage 4 cancer undergoing chemotherapy?
• Which statement is true regarding vesicant drugs management?
• In radiotherapy planning, which volume includes potential microscopic disease?
• Vinca alkaloids primarily affect cells in which phase?
• Which of the following is an example of an acute toxicity linked to chemotherapy causing local tissue damage from leakage?
• Which topical chemotherapy agent is commonly used to treat skin cancers?
• In radiotherapy planning, which statement correctly defines GTV, CTV, and PTV?
• Platinum drugs exert their cytotoxic effect primarily by which mechanism?
• Which statement describes how brachytherapy delivers radiation?
• One benefit of oral drug administration for chemotherapy is...
• What is the purpose of adding a boost to the tumor bed after whole-breast irradiation?
• Destruction of hair follicle cells leads to which effect?
• What is SBRT and its main advantage?
• What patient factors commonly necessitate chemotherapy dose adjustments?
• What is the mechanism of action of trastuzumab?
• Which gastrointestinal problem caused by chemotherapy occurs because of autonomic nervous system dysfunction?
• What is capecitabine and what is a characteristic toxicity?
• What is a typical external beam radiotherapy fraction size and total dose for curative intent in many solid tumors?
• Which mechanism best describes the action of vinca alkaloids?
• Which statement would the nurse include in the teaching for a patient experiencing stomatitis from chemotherapy?
• How is acute radiation dermatitis generally managed?
• What is a common side effect of chemotherapy mentioned in the material that affects energy and activity levels?
• The term for loss of taste is which?
• Bleomycin is typically administered by which route in chemotherapy?
• VEGF inhibitors primarily aim to:
• Which of the following is not a listed effect of chemotherapy cell destruction?
• Taxanes are which type of mitotic inhibitor and what do they do?
• Nitrosoureas are characterized by which property?
• Name two common platinum-based chemotherapeutic agents.
• Which statement made by a patient on chemotherapy with a low platelet count requires further nursing education?
• What is the primary goal of adjuvant chemotherapy after surgical resection of solid tumors?
• Which laboratory finding would most indicate nephrotoxicity risk in a patient receiving chemotherapy?
• What is the oxygen enhancement ratio and why is it important in radiotherapy?
• Which clinical manifestation is important for the nurse to monitor in a patient with thrombocytopenia from cancer treatment?
• Which class of chemotherapy agents works by binding directly to DNA to inhibit DNA synthesis?
• What is the CTCAE and what is it used for?
• What is the rationale for using concurrent chemoradiation in head and neck cancer?
• Intracavitary (pleural, peritoneal) chemotherapy may involve which of the following?
• Hand-foot syndrome is most commonly associated with which drug?
• Why is concurrent chemotherapy with radiotherapy used in locally advanced cancers?
• Purine and pyrimidine analogs are building blocks of nucleic acids and are targeted by which class?
• Why is hydration with aggressive IV fluids sometimes with mannitol essential when using cisplatin?
• Pregnancy is a consideration in chemotherapy planning because:
• What is the most common route of administration for chemotherapy?
• Which growth factor is a granulocyte colony-stimulating factor commonly used after chemotherapy?
• The nurse would recommend sunscreen to prevent which skin condition related to cancer treatments?
• Which of the following is NOT an example of an oral chemotherapy agent?
• Which intervention is listed as a measure to prevent uric acid nephropathy in chemotherapy patients?
• Which drug is given intramuscularly as an example?
• What is the concept of dose de-escalation in response to toxicity?
• Which information would the nurse include in teaching for a patient experiencing alopecia from chemotherapy?
• Odynophagia means which of the following?
• Methotrexate inhibits dihydrofolate reductase, leading to depletion of thymidine and purine synthesis. This action disrupts production of which type of biomolecules?
• What is the mechanism of action of methotrexate?
• Vesicant chemotherapy drugs are characterized by...
• Which statement best describes alkylating agents?
• Intrathecal chemotherapy examples include which drugs?
• Doxorubicin extravasation can cause which tissue injury?
• Margins added to account for setup and motion are included in which volume?
• Which regional route delivers chemotherapy to the brain's ventricular system?
• What is the primary goal of dose conformity in radiotherapy planning?
• Which regional route delivers chemotherapy into the cerebrospinal fluid?
• What is chemotherapy?
• What does extravasation refer to in IV chemotherapy?
• Which route of administration is capecitabine given?
• Which of the following are major concerns for chemotherapy delivered via the IV route?
• Which regional route administers chemotherapy via arteries to target a specific organ?
• What clinical sign commonly indicates neutropenia?
• Antimetabolites mimic naturally occurring substances. Which nucleic acid building blocks do they mimic?
• Which platinum agent is most associated with nephrotoxicity and ototoxicity?
• What does IMRT stand for and what is its main aim?
• Aside from cardiotoxicity, which toxicity is associated with doxorubicin?
• In BEP chemotherapy regimen, which drug is a platinum-based agent?
• Which imaging modality is used daily to verify patient alignment during radiotherapy?
• What is the effect of radiation therapy on cancer cells?
• A major radiation-related consideration in pediatric patients is which of the following?
• Which of the following is an acute hypersensitivity reaction associated with chemotherapy?
• Destruction of epithelial cells lining the GI tract commonly causes which condition?
• Which patient statement indicates an understanding of brachytherapy?
• Which action aligns with the care plan for a patient with chemotherapy-related nephrotoxicity?
• Which action is recommended to protect health care staff from radiation hazards when caring for a patient receiving brachytherapy?
• Which intervention from the following is listed as a possible measure to manage nephrotoxicity in chemotherapy patients?
• Which of the following is an example of an oral chemotherapy agent?
• Which statement would the nurse include in the teaching for a patient who is to receive radiation therapy for cancer?
• Which treatment goal is appropriate for a patient with stage 4 breast cancer, who has severe breast pain and is receiving chemotherapy?
• Which regional chemotherapy route is used to deliver drugs directly into the urinary bladder?
• Chemotherapy can cause reproductive problems due to damage to which organs?
• Which statement best contrasts irritant vs vesicant chemotherapy drugs?
• What is the major hematologic consequence of bone marrow suppression caused by chemotherapy?
• Which drug is listed as an intraarterial chemotherapy example?
• Perfusion chemotherapy examples are from which drug class?
• Which therapeutic measure listed is used to address nephrotoxicity from chemotherapy?
• Nitrosoureas have a notable property of crossing which barrier?
• Which acute toxicity is characterized by nausea and vomiting that occurs before chemotherapy starts (anticipatory)?
• Before radiation therapy can begin, imaging such as CT or MRI is used to plan treatment. Which option best describes this purpose?
• Which class includes vincristine and vinblastine, and what is a key toxicity?
• Which laboratory trend would support the presence of nephrotoxicity in a patient receiving chemotherapy?
• What strategy would the nurse suggest for a patient experiencing fatigue as a side effect of chemotherapy?
• Which type of food would you suggest to a patient with diarrhea caused by chemotherapy?
• Brachytherapy is best described as which type of radiation therapy?
• What is a major toxicity of doxorubicin and how is it mitigated?
• Hyperfractionation in radiotherapy is defined as delivering what?
• Which of the following is an example of endocrine therapy used for hormone receptor-positive breast cancer?
• Paclitaxel is best described as which type of agent and common toxicities?
• What is tumor lysis syndrome and which cancers are at highest risk?
• How is a complete response defined in RECIST 1.1?
• Mitotic inhibitors disrupt which cellular process?
• Which of the following is a delayed effect of chemotherapy that affects blood cell production?
• For a patient with osteogenic sarcoma, which route is commonly used to administer chemotherapy?
• Xerostomia is best described as which symptom?
• Which monoclonal antibody targets CD20 on B cells in non-Hodgkin lymphoma?
• The alpha/beta ratio used in BED calculations reflects tissue sensitivity to fractionation. Which statement is true?
• Anorexia describes which symptom?
• Why are spinal cord constraints critical in radiotherapy planning?
• Bevacizumab reduces tumor angiogenesis by inhibiting which target?
• In addition to mucositis, what is another common toxicity of antimetabolites such as 5-fluorouracil and capecitabine?
• Bleomycin's major pulmonary toxicity?
• Which complication would the nurse monitor for in a patient experiencing neutropenia from chemotherapy?
• How many days per week is external beam radiotherapy typically delivered in curative schedules?
• The BED concept helps compare different fractionation schemes by accounting for total dose and fraction size via which model?
• Which statement correctly differentiates neoadjuvant from adjuvant therapy?
• Neutropenia is defined by an absolute neutrophil count below which value?